{"data":{"company":{"name":"Serif 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xenograft, syngeneic, and transgenic mouse models relevant to platform and therapeutic programs.</li>\n<li>Contribute to study designs, study planning, and resource allocation of in vivo studies by working in close collaboration with head of Pharmacology.</li>\n<li>Perform animal procedures including blood collection, necropsy, tissue harvest, and homogenization, cell isolation, and test article administration through multiple routes.</li>\n<li>Establish and maintain strong relationships with vivarium and external CRO to ensure high quality and timely execution of studies.</li>\n<li>Perform dose calculations and prepare dosing formulations for rodent and NHP studies.</li>\n<li>Ensure study compliance with IACUC protocols, and company policies.</li>\n<li>Maintain accurate experimental records, study protocols and reports.</li>\n<li>Demonstrate scientific and technical expertise to advance in vivo studies through familiarity with scientific literature.</li>\n<li>Proactively recognize and develop creative solutions for emerging technical and scientific issues.</li>\n<li>Analyze relevant tolerability endpoints and effectively communicate results to stakeholders.</li>\n</ul>\n<p>Required Qualifications:</p>\n<ul>\n<li>M.S with 10+ or B.S with 12+ years industry experience, respectively.</li>\n<li>Proficient hands-on experience in mouse models of immunology, oncology and transgenic reporter models.</li>\n<li>Experience in writing IACUC protocols required.</li>\n<li>Experience performing in-vivo procedures in rodents, including dose preparation and administration of therapeutics and sample collection.</li>\n<li>Strong organizational, communication and interpersonal skills.</li>\n<li>Ability to thrive in a fast-paced, and rapidly growing biotech environment with changing priorities.</li>\n</ul>\n<p>Benefits:</p>\n<ul>\n<li>Healthcare coverage</li>\n<li>Annual incentive program</li>\n<li>Retirement benefits</li>\n</ul>","enriched_at":1793434451492},{"id":"job_f4fa57b0-1ac","title":"Associate Scientist, Bioanalytical Assays","source_url":"https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8920051002","location":"Cambridge, MA","job_type":"full-time","experience_level":"senior","work_arrangement":null,"category":"Research","description":"<p>We are searching for an experienced Associate Scientist to drive bio-analytical assays for a novel DNA platform.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>Execute and analyse bioassays to assess efficacy, safety, and biodistribution of novel nucleic acid therapeutics in rodents and NHPs.</li>\n<li>Contribute to scientific and technical perspectives to advance platform development.</li>\n<li>Develop, optimise, and execute ligand binding assays to support studies in-house and at CROs.</li>\n<li>Communicate experimental findings effectively in oral, written, and visual formats.</li>\n<li>Work independently and collaboratively in a 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benefits</li>\n</ul>\n<p>The salary range for this role is $96,000 - $126,500.</p>","enriched_at":1793434374445},{"id":"job_ec6ed0e6-8ad","title":"Laboratory Operations Associate","source_url":"https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8853174002","location":"Cambridge, MA","job_type":"full-time","experience_level":"mid","work_arrangement":"onsite","category":"Operations","description":"<p>We are seeking a highly organized and hands-on Laboratory Operations Associate to support sample management, inventory, and day-to-day operations for our CMC and broader laboratory teams.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>CMC Support: Work closely with the CMC team to build out and maintain their sample management and inventory system. Organize final cargo and support handoffs of materials to other teams across the company. Provide regular updates on cargo inventory status to the Director of CMC, Head of Analytics, Senior Manager of Operations, and other team leads. Partner with scientists and the Senior Manager of Operations to organize inventory and coordinate procurement of key enzymes, buffers, and other consumables.</li>\n</ul>\n<ul>\n<li>Lab Operations Support: Run decontamination and cleaning protocols on Fragment Analyzers and flow cytometers on a weekly basis. Complete daily “Lab Tasks” to maintain lab organization cleanliness, and readiness. Support lab space optimization efforts as the team grows within an increasingly confined footprint. Troubleshoot key laboratory equipment and support routine equipment upkeep. Perform Category B equipment maintenance (freezer defrosts, incubator PMs, centrifuge calibrations, pipette calibration scheduling, etc.). Provide procurement support for general lab consumables.</li>\n</ul>\n<ul>\n<li>Lab Onboarding Support: Assist in executing new lab member onboarding, including bench allocation; procurement of benchtop equipment and consumables (pipettes, centrifuges, freezers); Support fridge and freezer allocation; safety training checks; and small lab consumables procurement. Help ensure team members are set up efficiently to work safely and effectively in the lab.</li>\n</ul>\n<p>Education and Qualifications:</p>\n<ul>\n<li>BS degree in Biology, chemistry, Biochemistry or related field</li>\n<li>2+ years of experience in laboratory operations, sample management or both</li>\n<li>Hands-on bench experience at the Research Associate or Associate Scientist level</li>\n<li>Experience in sample management and/or laboratory operations (experience in both is a plus)</li>\n<li>Hands-on experience with cytometers, Fragment Analyzers, and chromatography instruments</li>\n<li>Strong communication skills and the ability to work cross-functionally with scientists and operations leadership</li>\n<li>Ability to lift up to 30 lbs</li>\n<li>Candidates with sample management experience who are looking to grow into a lab management role are strongly encouraged to apply</li>\n<li>Experience working with Benchling, specifically Workflows and Inventory is desirable. Experience with other LIMS or inventory systems is a plus.</li>\n</ul>","enriched_at":1793188759505},{"id":"job_909a9452-79b","title":"Associate Director, LNP Manufacturing","source_url":"https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8908668002","location":"Cambridge, MA","job_type":"full-time","experience_level":"senior","work_arrangement":"onsite","category":"Manufacturing","description":"<p>We are seeking an outstanding Associate Director to join us in ideating and building the next generation of Programmable Medicines and lead a team of talented scientists and engineers.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>Lead LNP scale-up from small R&amp;D formulations to NHP scale in support of a development candidate.</li>\n<li>Drive upstream and downstream process development, including mixing platforms (T-mix, impingement), TFF, and freeze/storage buffer optimization.</li>\n<li>Scale targeted LNPs (tLNPs), including conjugation, purification, and associated 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critical product attributes</li>\n<li>General understanding of molecular biology and nucleic acid therapeutics</li>\n<li>Experience managing and mentoring research associates and junior scientists</li>\n</ul>\n<p>Preferred Experience:</p>\n<ul>\n<li>Experience scaling in a GMP environment and managing CDMOs</li>\n<li>Experience taking LNPs to the clinic, including agency interactions</li>\n<li>Experience with tLNP conjugation at scale</li>\n<li>Lipid synthesis, purification, and compositional analysis</li>\n</ul>\n<p>The level of the role will be commensurate with the education and years of experience of the identified candidates.</p>\n<p>Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.</p>","enriched_at":1793183571354},{"id":"job_8eea6482-d62","title":"Senior Scientist, Bioanalytical Sciences","source_url":"https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8872070002","location":"Cambridge, MA","job_type":"full-time","experience_level":"senior","work_arrangement":"onsite","category":"Research","description":"<p>We are seeking a highly motivated and accomplished Sr. Scientist I with deep expertise in innate immunogenicity, and bioanalytical assay development, including ligand binding assays (LBA) and multi-color flow cytometry.</p>\n<p>In this role, you will lead the development, qualification, and implementation of various immunogenicity and LBAs that support both our platform and therapeutic programs, with a particular focus on characterizing innate immune responses to novel nucleic acid modalities.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>Design, develop and execute cell-based immunoassays, flow cytometry based assays and LBAs to assess immunogenicity to LNP delivered nucleic acid cargoes in vitro and in vivo</li>\n<li>Apply knowledge of innate 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Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits.</p>","enriched_at":1793091938445},{"id":"job_bf229f43-137","title":"Senior Scientist, Analytical Development and Quality Control","source_url":"https://job-boards.greenhouse.io/flagshippioneeringinc/jobs/8746157002","location":"Cambridge, MA","job_type":"full-time","experience_level":"senior","work_arrangement":null,"category":"Research","description":"<p>We are seeking a highly motivated and experienced candidate for a role of Senior Scientist on the Analytical Development and Quality Control team.</p>\n<p>This candidate will lead method development, optimization, and qualification efforts to support characterization of novel nucleic acid therapeutics and LNP delivery vehicles, and will mentor junior team members as part of this role.</p>\n<p>Key Responsibilities:</p>\n<ul>\n<li>Lead the team&#39;s advancement of platform development and play a vital role in shaping our analytical capabilities.</li>\n<li>Step into benchwork to execute platform goals with tenacity and agility, while providing technical direction and mentorship to junior team members.</li>\n<li>Lead method development and implementation to support nucleic acid cargo and LNP product release, stability and characterization.</li>\n<li>Lead experimental studies to optimize specificity, sensitivity, precision, accuracy, and/or linearity of analytical methods.</li>\n<li>Troubleshoot assay development and instrument operation issues, serving as a technical resource for the broader team.</li>\n<li>Experimental planning, study design and scheduling of development projects as well as routine testing across programs.</li>\n<li>Support day-to-day execution of analytical analysis for process development activities to ensure robust process and product characterization.</li>\n<li>Work independently and collaboratively in a multidisciplinary team environment, providing technical guidance and mentorship to junior colleagues.</li>\n<li>Analyze, troubleshoot, and communicate experimental findings clearly and succinctly in oral, written, and visual formats to internal teams and cross-functional stakeholders.</li>\n<li>Provide technical input to support regulatory filings.</li>\n<li>Author and manage protocols, laboratory data, and technical reports.</li>\n</ul>\n<p>Qualifications:</p>\n<ul>\n<li>Degree in Chemistry, Biochemical Engineering, Biochemistry, Molecular Biology, Chemical Engineering, Biotechnology or related field. B.S. degree with 14+ years, M.S. degree with 12+, or Ph.D. with 5+ years of relevant industry experience.</li>\n<li>Prior hands-on experience working with mRNA/DNA cargo and LNP products.</li>\n<li>Demonstrated technical expertise in HPLC separations or LC-MS, with a track record of independently developing and troubleshooting analytical methods.</li>\n<li>Experience with plate-based assays is a plus.</li>\n<li>Proven ability to independently design, execute, and troubleshoot complex experiments.</li>\n<li>Experience mentoring, training, or providing technical guidance to junior staff is desired.</li>\n<li>Strong communication and organization skills; good working knowledge of Benchling, MS Office, JMP, GraphPad, Empower, Chromeleon.</li>\n</ul>\n<p>Benefits:</p>\n<ul>\n<li>Healthcare coverage</li>\n<li>Annual incentive program</li>\n<li>Retirement benefits</li>\n</ul>\n<p>Salary range: $126,000 - $181,500</p>","enriched_at":1793091902535}],"category_normalised":[{"category":"research","count":4},{"category":"operations","count":1},{"category":"manufacturing","count":1}],"velocity":{"weeks":[{"week_start":"2026-10-26","count":6}],"trend":"stable","wow_pct":0},"momentum":{"recent_14d":6,"prior_14d":0,"growth_pct":0,"classification":"stable"},"salary_vs_industry":{"company_median":137625,"industry_median":null,"percentile":null,"sample_size":6,"by_region":[{"region":"United Kingdom","company_median":137625,"industry_median":null,"sample":6}],"transparency_pct":100,"industry_transparency_pct":0,"transparency_warning":false},"market_share":{"company_jobs":6,"industry_total":6,"share_pct":100,"rank":1,"peer_count":1},"ai_exposure":null,"peer_set":[],"skills_lq":[],"geographic_shift":{"current":[{"region":"United Kingdom","count":6,"share_pct":100}],"emerging":[{"region":"United Kingdom","recent_30d":6,"prior_30d":0,"growth_pct":100}],"shrinking":[]},"seniority_anomalies":{"exec_recent_30d":1,"exec_prior_90d_avg":0,"exec_growth_pct":100,"notable_exec_hires":[{"title":"Associate Director, LNP Manufacturing","location":"Cambridge, MA","posted_at":"2026-10-28"}]},"posting_dynamics":{"median_days_open":null,"industry_median_days_open":null,"long_open_count":0,"closure_rate_pct":0}}}}